In mysql, you can insert multiple rows to a table in one query for n > 0:
INSERT INTO tbl_name (a,b,c) VALUES(1,2,3),(4,5,6),(7,8,9), ..., (n-2, n-1, n);
These answers are outdated. bulk_create has been brought in Django 1.4:
bulk_create
https://docs.djangoproject.com/en/dev/ref/models/querysets/#bulk-create