I honestly cannot recall a bug that I couldn't fix. It may cause a lot of refactoring, or may take a while, but I've never had one that I can't get rid of. If it takes me more than an hour to track it down then it's almost always something really stupid and small like looking right past that : that should've been a ;, etc.
In python, if I'm using an editor that isn't mine, or maybe it's someone else's code, I use retab! in vim, or paste into something like pastie to check indentation (if I don't have vim available).
If it's not a crasher/deal breaker, then I move on and come back with a fresh pair of eyes.
Oh, and you can never, ever have too much logging.
