Animated .GIF vs Spritesheet + JS/CSS

Question

Which will scale best for performance, file-size, (and my sanity): Animated .gifs or a spritesheet with animations using CSS (and JS when need be)?

File

Answer 1

Gif animations can repeat sprites, they can also use partial frame updates, and positioning the same sprite at different positions. If you simply want to display a non-interactive animation I'd say animated gifs have all the advantages, except for colour, you are forced to use a 256 colour palette.

I remember using Microsoft GIF Animator, that is certainly easy to use. I don't know anything about Photoscape, but word on the net is that that is a good slightly more heavy alternative.