Well, someone has to say it, so here goes:
Lisp is regarded by some as the domain specific language for any domain. A well-supported and very extensible DSL at that.
In some cases, fashioning a DSL from Lisp (or a similar language such as Haskell) could actually provide a lot of power with minimal effort, and thus would be quite worthwhile. DSLs do not always need to be big maintenance burdens.
