To find out if two molecules can fit together. When developing drugs one is often interested in seeing if the drug molecules can fit into larger molecules in the body. The problem with determining whether this is possible is that molecules are not static. Different parts of the molecule can rotate around their chemical bindings so that a molecule can change into quite a lot of different shapes.
Each shape can be said to represent a point in a space consisting of shapes. Solving this problem involves finding a path through this space. You can do that by creating a roadmap through space, which is essentially a graph consisting of legal shapes and saying which shape a shape can turn into. By using a A* graph search algorithm through this roadmap you can find a solution.
Okay that was a lot of babble that perhaps wasn't very understandable or clear. But my point was that graphs pop up in all kinds of problems.
