How to Handle below IE Popup in Selenium

You can try to accept the alert via selenium. Not sure what language you're using but the following Java method should accept the alert and let you move on with your life.
public void checkAlert()
{
try
{
// Wait for the alert to show
WebDriverWait wait = new WebDriverWait(driver, 2);
wait.until(ExpectedConditions.alertIsPresent());
driver.switchTo().alert().accept();
}
catch (Exception e)
{
//exception handling
}
}
You'll want to add import org.openqa.selenium.Alert; to your imports (again if you're using Java)