I just installed VS 2015, the installation was finish (after some fail time caused by the slow network, I run setup again).
I create a project as Adroid > A
Sometimes the physical Android device gets confused about versions.
On the device, to go settings | Applications Manager | All applications.
Manually delete your application. Manually delete "Mono Shared Runtime" (don't worry it will reinstall during deploy)
Make any change in your project so it is seen as altered and needing to be recompiled: Add a new blank-line to a .cs file or something.
Build Debug/deploy