EDIT: After waited a while and didn\'t get anything yet, I\'ve decided to do shortcut disable thingy only for IE now. Is there a possib
You can try creating an event handler for keydown event, check on the keyCode and prevent its default action if needed. However this will not work in all browsers.
An example for Firefox (canceling "Print" short key, verified):
document.addEventListener("keydown", function(oEvent) {
if (oEvent.keyCode == 80 && oEvent.ctrlKey)
oEvent.preventDefault();
}, false)