Many people experienced issues with memory usage when switching their Rails app from Ruby 2.0 to Ruby 2.1 on Heroku. For example, see Memory usage increase with Ruby 2.1 ver
Ruby 2.2-2.3 introduced another bug for multithreaded C-based ruby installations https://evilmartians.com/chronicles/ruby-2_2-oom,
basically, if stars align badly the GC turns off :P and with some sites stars align badly couple times a day, we still use Ruby 2.0 and are waiting for 2.3.5 for the fix from the blog to come out