I ran out of disk space and had to clean up the folders on my hard disk. After the cleanup, when I run Xcode, the simulator is not coming up. I am not able to select a sim
I was able to delete my simulator devices and re-install them by following this excerpt written for a user that was missing their simulator:
Open the Xcode > Open Developer Tool > iOS Simulator menu (if you get a pop up error just dismiss it). Once in the Simulator go to Hardware > Device > Manage Devices. Delete everything listed under simulator. Reboot your machine. After that navigate back to Manage Devices in the simulator and click the plus to add back your simulators. Then the iOS 8 simulators will show up. Hope that also helps you.
Here is where it came from: http://www.reddit.com/r/iOSProgramming/comments/2b9j2p/xcode_6_missing_ios_8_simulator/