If you ever want to delete more than one columns, you just pass indices of columns you want deleted as a list, like this:
>>> a = np.arange(12).reshape(3,4)
>>> a
array([[ 0, 1, 2, 3],
[ 4, 5, 6, 7],
[ 8, 9, 10, 11]])
>>> np.delete(a, [1,3], axis=1)
array([[ 0, 2],
[ 4, 6],
[ 8, 10]])