Package management initialization failed: Access Denied Error when opening Visual Studio 2017

Question

I\'m getting the following error when opening VS 2017 on Windows 7 64-bit:

Package management initialization failed: Access Denied.

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Answer 1

I had the same problem and when I looked at

 C:\Users\UserName\AppData\Local\Microsoft\VisualStudio 

I noticed that I had miltiple versions of visual studio meaning the current update might not have been successfull, as I was not able to delete the file that @Neil Patro says, I simply deleted the entire updates and all was ok. I guess adding this as an answer might help.