Recently I set up a new EC2 instance. The next day I was not able to connect to my instance via ssh. I could connect and disconnect the day before, I am sure I did nothing.
Often times, you should use the default user name for the AMI that you used to launch your instance:
For Amazon Linux 2 or the Amazon Linux AMI, the user name is
ec2-user.
For a CentOS AMI, the user name is centos.
For a Debian AMI, the user name is admin or root.
For a Fedora AMI, the user name is ec2-user or fedora.
For a RHEL AMI, the user name is ec2-user or root.
For a SUSE AMI, the user name is ec2-user or root.
For an Ubuntu AMI, the user name is ubuntu.
Otherwise, if ec2-user and root don't work, check with the AMI provider.
https://docs.aws.amazon.com/AWSEC2/latest/UserGuide/connection-prereqs.html#connection-prereqs-get-info-about-instance