Pass a variable to your template, maybe called title. Then replace your title block with {{ title }}. To pass this into your template in your view make sure you have:
def myview(request):
t = loader.get_template("mypage.html")
title = "My Title"
c = Context({"title" : title })
HttpResponse(t.render(c))
Then in your template you will have:
{{ title }}
{{ title }}}
See also: How to repeat a "block" in a django template