I understand that I can set the option on any specific instance, however what I would really like is to set something up php.ini or somewhere similar which will handle this
I found the answer here (in the user notes): http://php.net/manual/en/function.curl-setopt.php
Just add this to you .ini (note: you cannot use ini_set, although I don't know why you would want to. Thanks @Carlton):
curl.cainfo=c:\php\cacert.pem
And get that file from: http://curl.haxx.se/docs/caextract.html
Works and you aren't opening yourself up for MITM attacks