Until very recently, instruments worked fine. I don\'t know what I did to make it mad, but now it won\'t attach to any device that I try to Profile with; no device at all. I
There was a discussion on the apple developer forums about this issue:
Instruments does not work on Xcode 4 with device
It appears that different Apple products will change/update the MobileDevice framework. Some of these updates break the Instruments integration.
To fix this on my own machine, I installed the iTunes 10.5 beta v6. Fire up XCode, and I'm back in business Instrumenting on my device.