I have a pandas data frame and group it by two columns (for example col1 and col2). For fixed values of col1 and col2 (i.
col1
col2
In [17]: df Out[17]: 0 1 2 0 1 1 1 1 1 1 1 2 1 1 2 3 1 2 3 4 1 2 3 5 1 2 3 6 2 1 1 7 2 1 2 8 2 1 3 9 2 2 3 10 2 2 3 11 2 2 3 In [19]: df.groupby([0,1])[2].apply(lambda x: len(x.unique())) Out[19]: 0 1 1 1 2 2 1 2 1 3 2 1 dtype: int64