How can I profile Signed Assemblies with VS 2010 or VS 2013

Question

I have a website that uses AjaxControlToolkit.dll and Log4Net.dll.

When I try to run the performance profiling tool in VS 2010 on it it gives me the following warnin

Answer 1

The profiler probably changes the assembly and because it was previously signed. Apparently you need to add a post-instrument action that re-signs the assembly.

This could be a problem because you do not have the sn file that was used to sign the 3rd party assemblies.