I\'ve been running my app on an iPhone 5 /iOS 6, but when I try to run it on an iPhone 4S / iOS6 I get \"The run destination iOS Device is not valid for running the scheme N
Switching to a different USB port and restarting Xcode solved the problem. Experienced this issue on iMac running Xcode 9.1 whenever I tried connecting any iOS device to one specific USB port. If your USB ports stopped working, check this.