It was working like a charm before the update from Mountain Lion.
After the update it is broken and I cannot get the environment up again.
Does anybody know
Building on Ned's answer:
Since I don't want to use sudo to install packages (I am using virtual environments) or affect my golbal environment, I added the two variables to the single execution of pip install:
pip install
CFLAGS=-Qunused-arguments CPPFLAGS=-Qunused-arguments pip install -r requirements.txt