After having installed the iPhone SDK 3.1.2, Interface Builder is not in sync with Xcode anymore. The light indicator at the bottom of the XIB window is grey. IB doesn\'t
I have been having the same problem and it's been driving me nuts.
Bizarrely, it seems to be caused by opening your project using the File > Open Recent Project menu in Xcode, or by using the Recent Documents list in the Xcode welcome screen.
If I double-click the project file in the Finder to open it or choose the project from the Recent Items menu in the Apple menu, Xcode's connection to Interface Builder is intact.
Does that help you?