The title really says it all. A friend of mine told me he knows someone who can program in binary. I\'ve never heard of someone programming in binary and a few quick Google
There isn't much call for it any more, but it has been done. There was a time when code could be entered into a system in binary from the front console. It was error prone.
I used to have a very short uudecoe program encoded in ASCII which could be prefixed to a UUEncoded file. The resulting file would be self-extracting and could be emailed around. I would expect the machine code was hand done. I can't find it, and don't have a use for it even if I could.