I am looking for something like uWSGI + django autoreload mode for Flask.
If you're configuring uwsgi with command arguments, pass --py-autoreload=1:
uwsgi
--py-autoreload=1
uwsgi --py-autoreload=1
If you're using a .ini file to configure uwsgi and using uwsgi --ini, add the following to your .ini file:
.ini
uwsgi --ini
py-autoreload = 1