I stumbled upon a tool that generates P/Invoke signatures for Microsoft\'s own unmanaged DLLs: PInvoke Interop Assistant
Is there a similar tool that will generate P
I use PInvoke Interop Assistant for unmanaged DLLs by using the third tab in the UI, marked "SigImp Translate Snippet". Simply copy-and-paste your header into the "Native Code Snippet" window and press Generate (or turn on Auto Generate). As an illustration here's some code from a question of mine. Note that for some reason errors don't appear in the Error panel but as comments at the top of the generated code.
As several people have already said, the generated code should be used as a guide - you may well have to make changes to get exactly what you want.