We use Enterprise Architect for our DB definitions. We include stored procedures, triggers, and all table definitions defined in UML. The three brilliant features of the program are:
- Import UML Diagrams from an ODBC Connection.
- Generate SQL Scripts (DDL) for the entire DB at once
- Generate Custom Templated Documentation of your DB.
You can edit your class / table definitions within the UML tool, and generate a fully descriptive with pictures included document. The autogenerated document can be in multiple formats including MSWord. We have just less than 100 tables in our schema, and it's quite managable.
I've never been more impressed with any other tool in my 10+ years as a developer. EA supports Oracle, MySQL, SQL Server (multiple versions), PostGreSQL, Interbase, DB2, and Access in one fell swoop. Any time I've had problems, their forums have answered my problems promptly. Highly recommended!!
When DB changes come in, we make then in EA, generate the SQL, and check it into our version control (svn). We use Hudson for building, and it auto-builds the database from scripts when it sees you've modified the checked-in sql.
(Mostly stolen from another answer of mine)