This answer shows how I locate code to optimize.
Suppose there is some line of code you could replace, and it is costing, say, 40% of the time.
Then it resides on the call stack 40% of the time.
If you take 10 samples of the call stack, it will appear on 4 of them, give or take.
It really doesn't matter how many samples show it.
If it appears on two or more, and if you can replace it, you will save whatever time it costs.