I really like the ability to edit javascript in the chrome debugger however, I find that it can be really problematic getting the debugger to re-fetch the JavaScript from th
If you're running a local server on Apache, you can get what look like caching problems. This happened to me when I had a Apache server running under Vagrant (in virtualbox).
Just add the following lines to your config file (/etc/httpd/conf/httpd.conf or equivalent):
#Disable image serving for network mounted drive
EnableSendfile off
Note that it's worth searching through the config file to see if EnableSendfile is set to on anywhere else.