Fast alternative to grep -f

Question

file.contain.query.txt

ENST001

ENST002

ENST003

file.to.search.in.txt

ENST001  90

ENST002  80

ENST004  50

Answer 1

This Perl code may helps you:

use strict;
open my $file1, "<", "file.contain.query.txt" or die $!;
open my $file2, "<", "file.to.search.in.txt" or die $!;

my %KEYS = ();
# Hash %KEYS marks the filtered keys by "file.contain.query.txt" file

while(my $line=<$file1>) {
    chomp $line;
    $KEYS{$line} = 1;
}

while(my $line=<$file2>) {
    if( $line =~ /(\w+)\s+(\d+)/ ) {
        print "$1 $2\n" if $KEYS{$1};
    }
}

close $file1;
close $file2;