I deployed my application in App engine successfully. However, when I try to access my API, I receive the following message:
Error: Server Error Th
The first traceback appears to suggest that grpc is somehow involved, and that's a problem. According to comments on issue 149 grpc is not yet supported on GAE standard environment.
But since you're on the GAE standard environment you should really use the recommended, GAE-optimized (and more feature-rich) NDB Client Library to access the datastore, not the generic google.cloud.datastore one (which might indeed include features not meeting the standard env sandbox restrictions).