I am having issues with javascript files not decompressing in IIS7 and stylesheets not loading properly.
I can fix this issue by turning off Static compression in II
I have narrowed this issue down to the web site using Blowery HttpCompression.
It seems that with .net 4.5 Blowery and IIS no longer play together nicely and the static content seems to be compressed twice, once by Blowery and once by IIS.
The above is a guess but one think I do know is that be removing Blowery the website works fine again.