SQL: search/replace but only the first time a value appears in record

Question

I have html content in the post_content column.

I want to search and replace A with B but only the first time A appears in the record as it may appear more than onc

Answer 1

To keep the sample of gjreda a bit more simple use this:

UPDATE wp_post
    SET post_content =
            CONCAT(
                REPLACE(LEFT(post_content, 1), 'A', 'B'),
                SUBSTRING(post_content, 2)
            ) 
    WHERE post_content LIKE 'A%';