Operation could destabilize the runtime in StructureMap

Question

I am getting this error in one of my ASP.NET 4.5 MVC application on my local machine. Other applications setup with ASP.NET 4.5 and using StructureMap work fine.

Answer 1

KB2748645 does not apply for Windows 8/8.1/10. In this case, you can try : Run -> Turn Windows features on or off -> reinstall .NET Framework 4.5 & IIS .

Note: if you have ANTS 8.5 Performance Profiler, disable & de-attach it.

It helped in my case.