I am trying to connect to Neptune DB in AWS Instance from my local machine in office,like connecting RDS from office.Is it possible to connect Neptune db from local machine?
As already mentioned you can't access directly outside your VPC.
The following link describes another solution using a SSH tunnel: connecting-to-aws-neptune-from-local-environment.
I find it much easier for testing and development purpose.
You can create the SSH tunnel with Putty as well.