I have these groupboxes:

I want to run some code according to checked
You should take some look at the CheckedChanged event to register the corresponding event handler and store the Checked radio button state in some variable. However, I would like to use LINQ here just because you have just some RadioButtons which makes the cost of looping acceptable:
var checkedRadio = new []{groupBox1, groupBox2}
.SelectMany(g=>g.Controls.OfType()
.Where(r=>r.Checked))
// Print name
foreach(var c in checkedRadio)
System.Diagnostics.Debug.Print(c.Name);