I was developing just fine in VS 2008 and testing my ASP.NET web site on my development server when suddenly I was unable to run my web site anymore. As soon as I hit F5, th
I had this same problem today and found a solution so I thought I would add my two cents:
My particular problem was that I would get the "Port in use" error message even though the development server was clearly running and I was able to use the application on it. As it transpired, I was working on a Web Service at the time and happened to have the design view open - without realising. It was this web service's design view that was trying to launch the development server - which is why I couldn't type a single character of code without getting the error.
Close your Web Service's design view... problem solved.
I sincerely hope this helps someone else someday too.
Cheers
Iain