Setup targeting both x86 and x64?

Question

I have a program that requires both x64 and x86 dlls (it figures out which ones it needs at run time), but when trying to create a setup, it complains:

Answer 1

.Net has an "Any CPU" option. It's tempting to think of it as more of a "generic" option that's going to only use the lesser x86 features, but really it lets the JIT compiler on each machine pick the appropriate cpu type for that machine.

The only time you shouldn't use it is if you know you have dependencies or requirements that aren't good for one architecture or the other. For example: you know you need a lot of ram, you have a dependancy on a 32-bit native dll, or you want to pre-compile the app.

There's a danger here because you have a platform-specific dll dependancy. But you have dlls for both types and it sounds like you know how to pick the right one at runtime. So will the 'Any CPU' option work for you?