What does ERR_SPDY_PROTOCOL_ERROR mean in nginx?

Question

I and a few of my colleagues got the net::ERR_SPDY_PROTOCOL_ERROR error.

We use ngnix version 1.8.0. The error is not stable (hard to replicate), and t

Answer 1

As with the OP, this was an intermittent issue for me and only happening on AJAX requests > 2mb in size.

The problem started occurring after we moved from an AWS classic ELB to ALB.

I solved this by uninstalling Chrome, deleting my user profile (On mac delete the contents of ~/Library/Application Support/Google/Chrome), then reinstalling.