The negative margin would help a lot!
The html DOM looks like below:
Left Images or something else
And the CSS:
.main {
float:left;
width:100%;
}
.main_body{
margin-left:210px;
height:200px;
}
.left{
float:left;
width:200px;
height:200px;
margin-left:-100%;
}
The main_body will responsive it's with, may it helps you!