I\'m currently using this regex ^[A-Z0-9 _]*$ to accept letters, numbers, spaces and underscores. I need to modify it to require at least one number or letter s
You simply need to specify your current RE, followed by a letter/number followed by your current RE again:
^[A-Z0-9 _]*[A-Z0-9][A-Z0-9 _]*$
Since you've now stated they're Javascript REs, there's a useful site here where you can test the RE against input data.
If you want lowercase letters as well:
^[A-Za-z0-9 _]*[A-Za-z0-9][A-Za-z0-9 _]*$