Does anyone know the answer and/or have an opinion about this?
Since tuples would normally not be very large, I would assume it would make more sense to use structs
I don't know but if you have ever used F# Tuples are part of the language. If I made a .dll and returned a type of Tuples it be nice to have a type to put that in. I suspect now that F# is part of the language (.Net 4) some modifications to CLR were made to accommodate some common structures in F#
From http://en.wikibooks.org/wiki/F_Sharp_Programming/Tuples_and_Records
let scalarMultiply (s : float) (a, b, c) = (a * s, b * s, c * s);;
val scalarMultiply : float -> float * float * float -> float * float * float
scalarMultiply 5.0 (6.0, 10.0, 20.0);;
val it : float * float * float = (30.0, 50.0, 100.0)