We have here an asp.net 3.5 application using NTLM based windows authentication. The system runs on a private network that actually distributed over different geographic pla
On a related topic; if you are using IIS7.0 and kerberos authentication it appears AuthPersistNonNTLM=true can be used to avoid 401 round-trips for each request.
http://msdn.microsoft.com/en-us/library/aa347548(VS.90).aspx
http://blogs.technet.com/b/configurationmgr/archive/2010/06/03/solution-you-may-experience-slow-performance-when-using-bits-and-kerberos-authentication-on-configmgr-2007-distribution-points.aspx