I have a situation very much like the one at ImportError: DLL load failed: %1 is not a valid Win32 application, but the answer there isn\'t working for me.
My Python
I had the same problem. Here's what I did:
I downloaded pywin32 Wheel file from here, then
I uninstalled the pywin32 module. To uninstall execute the following command in Command Prompt.
pip uninstall pywin32
Then, I reinstalled pywin32. To install it, open the Command Prompt in the same directory where the pywin32 wheel file lies. Then execute the following command.
pip install
Wheel file will be like: piwin32-XXX-cpXX-none-win32.whl
It solvs the problem for me. You may also like to give it a try. Hope it work for you as well.