After upgrading macOS to Catalina, my Anaconda installation was helpfully reconfigured by Apple. Advice from the Anaconda website suggested a fresh install was the best way
My code didn't work at all after Catalina update. The simplest partial solution that I found was to copy all files containing the scripts in a new folder. That works at least to run the codes, but I still dealing with annoying message to allow access to my files.