I want to check if:
Is it possible to check this with one if statement?
You can simply use !empty:
if (!empty($arr['field'])) {
...
}
This is precisely equivalent to your conditions by DeMorgan's law. From PHP's documentation, empty is true iff a variable is not set or equivalent to FALSE:
isset(x) && x
!(!isset(x) || !x)
!empty(x)
As you can see, all three of these statements are logically equivalent.