Consider this code (node v5.0.0)
const a = Math.pow(2, 53)
const b = Math.pow(2, 53) + 1
const c = Math.pow(2, 53) + 2
console.log(a === b) // true
console.
Number.MAX_VALUE will tell you the largest floating-point value representable in your JS implementation. The answer will likely be: 1.7976931348623157e+308. But that doesn't mean that every integer up to 10^308 can be represented exactly. As your example code shows, beyond 2^53 only even numbers can be represented, and as you go farther out on the number line the gaps get much wider.
If you need exact integers larger than 2^53, you probably want to work with a bignum package, which allows for arbitrarily large integers (within the bounds of available memory). Two packages that I happen to know are:
BigInt by Leemon
and
Crunch