Row-wise sum of values grouped by columns with same name

Question

I have a data frame where several columns may have the same name. In this small example, both column \"A\" and \"G\" occur twice:

    A  C  G  A  G  T
1   1          


        

Answer 1

We can transpose dat , calculate rowsum per group (colnames of the original dat), then transpose the result back to original structure.

t(rowsum(t(dat), group = colnames(dat), na.rm = T))
#  A C G T
#1 1 0 1 0
#2 4 0 6 0
#3 0 1 0 1
#4 2 0 1 0
#5 1 0 1 0
#6 0 1 0 1
#7 0 1 0 1