Ignoring 16-bit stuff, VBA can be run on 32 or 64-bit Office hosts. 64-bit Office can only be run on a 64-bit OS, whereas yo
A LongPtr is always correct for your process. You do not need to worry about its size. You do not need the WIN64 constant to use it. In fact, the only constant you normally need is VBA7 that tells you whether the LongPtr is even available. If it is, use it, if it's not, you are definitely x86 so use Long.
Additionally, Windows x64 has an entire compatibility layer called WoW64. As a 32-bit app running on 64-bit Windows, you do not notice anything and you run as if the OS was 32-bit. Your pointer size is four bytes, your pointer-sized data types such as HWNDs are four bytes, so again, you do not need to worry about any of that if you only consult VBA7 and correctly place LongPtr in all places where a pointer-sized argument must appear.
So, for routine things inside your process, and for interacting with the OS and its objects, you don't need to worry about either your own or the OS'es bitness, and you don't need the WIN64 constant either.
Now, you specifically mention obtaining and using pointers that are valid for processes with different bitness than your own. Yes, that might be a problem, but this problem is not specific to VBA.
If, as a VBA app, you find yourself in a need to read memory of an arbitrary process of arbitrary bitness, you do need to compare your own bitness to its bitness. At this point you could make use of the WIN64 constant, but it's much more convenient in this case to check the Len(long_ptr_variable) at runtime than to have separate code branches.
Having made the test,
But note that even in this case, you don't care about the OS bitness or the WIN64 const either! You only care about your process bitness vs the other process bitness.