I know about Workspaces recently introduced in DevTools but that is not that i need. For example: page uses jquery that is loaded from CDN, i modify jquery library code, pre
As far as I can tell, there's no way to do this in Chrome's DevTools. You should look through the documentation about saving and making local changes. The only thing that seems to persist through reloads is snippets... but it doesn't seem like that's what you want.
If ever a solution for this is made... I want it. For now, it seems the best you can do is content scripts and the like.