I found a solution to add files in library.zip via: Extend py2exe to copy files to the zipfile where pkg_resources can load them.
I can access to my file when library
Thank you but I found the solution
my_data = pkg_resources.resource_stream("__main__",sys.executable) # get lib.zip file
zip = zipfile.ZipFile(my_data)
data = zip.read("foo/media/doc.pdf") # get my data on lib.zip
file = open(output_name, 'wb')
file.write(data) # write it on a file
file.close()
Best Regards