Since the upgrade to iOS 6, we are seeing Safari\'s web view take the liberty of caching $.ajax calls. This is in the context of a PhoneGap application so it is
Depending on the app you can trouble shoot the issue now in iOS 6 using Safari>Advanced>Web Inspector so that is helpful with this situation.
Connect the phone to Safari on a Mac an then use the developer menu to trouble shoot the web app.
Clear the website data on the iPhone after update to iOS6, including specific to the app using a Web View. Only one app had an issue and this solved it during IOS6 Beta testing way back, since then no real problems.
You may need to look at your app as well, check out NSURLCache if in a WebView in a custom app.
https://developer.apple.com/library/ios/#documentation/Cocoa/Reference/Foundation/Classes/NSURLCache_Class/Reference/Reference.html#//apple_ref/doc/uid/TP40003754
I guess depending on the true nature of your problem, implementation, etc. ..
Ref: $.ajax calls